Crestor Generic: Leading Cholesterol Fighter
It is very likely that you have heard that cholesterol is unhealthy, that this is something because of which older people suffer from atherosclerosis. If you go a little deeper into this topic, it turns out that there is “good” and “bad” cholesterol, some strange plaques that stick to the walls of our blood vessels, and other obscure things that make it seem like something already hurts you, and you start looking suspiciously at your daily omelet. In this article, we will try to sort out what bad cholesterol is and how to lower its level in the body. In particular, we will pay attention to a widely used drug Crestor and its generics.
What Is “Bad” Cholesterol?
Cholesterol has long been considered the main component of deposits on the walls of arteries (cholesterol plaques). However, later scientists found that cholesterol was not an independent substance. It binds to certain proteins, forming protein-fat complexes, or lipoproteins. There are two main types of lipoproteins: low density lipoproteins (LDL) and high density lipoproteins (HDL). It is this or that protein that gives these particles certain properties. In HDL, a protein of one type determines the property of a particle to take cholesterol from deposits in the walls of blood vessels and send it to the liver for processing. At the same time, another type of protein in LDL affects cholesterol so that its loose molecules easily attach to the walls of blood vessels and form a plaque there.
Thus, cholesterol itself is not the cause of atherosclerosis. This disease occurs due to the ratio of HDL to LDL in the blood, in which LDL is greater than HDL. Absolutely avoiding cholesterol doesn’t make sense, since our body needs it for the synthesis of steroids, vitamin D, as well as for the digestion of fatty foods.
Despite the fact that cholesterol enters our body with food of animal origin, very often the level of “bad” cholesterol is much higher in people who are limited to consuming meat products, or even are absolute vegetarians. This is because the levels of HDL and LDL in our body depend primarily on genetic factors, and only then on lifestyle, physical activity and consumed food. Of course, this doesn’t mean that you can eat tons of fatty meat and cream without being afraid to raise your level of bad cholesterol, however, it should be borne in mind that some foods that don’t contain cholesterol at all still lead to an increase in its level in the body, for example, sweets in large quantities.
How To Combat High Cholesterol?
First of all, in order to maintain a normal level of cholesterol in the blood, it is necessary to adhere to a healthy lifestyle: to be physically active, play sports, eat fiber-rich foods (fruits, vegetables, whole grain cereal), as well as those foods that contain unsaturated fatty acids (olive oil, fish oil, linseed oil, flax seeds, nuts). Of course, normalization of body weight is perhaps the first thing you should achieve if you want to be healthy. Those people who have problems with cholesterol level can turn their attention to a drug like Crestor. The main active ingredient of Crestor is rosuvastatin. This substance belongs to statins – a class of drugs that suppress the action of the enzyme HMG-CoA reductase. This enzyme is an important link at the very beginning of the chain of 37 reactions that result in the formation of cholesterol. The use of rosuvastatin as a means to reduce “bad” cholesterol is approved in most countries of the world. In fact, it is the most common statin that is used against atherosclerosis.
By lowering cholesterol, Crestor helps reduce the risk of stroke and heart attack, and reduces the likelihood of heart in men over 50 and women over 60 years old.
Is Crestor Safe?
Crestor entered the pharmaceutical market in early 200s. It is important that among the usual clinical trials of the effectiveness of rosuvastatin, there were also double-blind, randomized, placebo-controlled trials within the frames of the GALAXY program, which eliminated the possibility of self-hypnosis among subjects. As a result, neither subjects nor experimenters knew who was being treated with what, and the distribution among the groups was random. Another comprehensive study of this active substance under the AURORA program was carried out in 25 countries and confirmed its high effectiveness. However, rosuvastatin, like all other statin drugs, is more than a serious medication, and it is not possible to claim that it is safe. It can cause many side effects, and for some patients, Crestor may be contraindicated. For example, rosuvastatin is prohibited for patients who suffer from liver or kidney failure, diabetes, thyroid disorder, who are breastfeeding a baby, for those who drink alcohol. The full list of contraindications can be found in the instruction for use. It is undesirable to combine Crestor with drugs such as HIV protease inhibitors and cyclosporine. Some people, in particular Asians, are more sensitive to this medicine due to the features of their genes, and it is advisable for them to lower the dosage, not exceeding 10 mg per day. In general, before taking this drug, it is recommended to consult a doctor and conduct an assessment of cardiovascular risk. It is also advised that you carefully read the instructions before use.
Please note that despite taking Crestor, to effectively lower blood cholesterol, you must adhere to a hypocholesterolemic diet, i.e. avoid consuming foods that contain significant amounts of cholesterol. Only then taking this medicine will not be in vain.
What Is Crestor Generic?
Crestor is a rather expensive medicine, especially as doctors usually prescribe a fairly long course of treatment. In this case, you can use the generics of Crestor. They can be sold under a variety of names that have nothing to do with the word “Crestor”, but they all share the fact that their active ingredient is rosuvastatin. Thus, all of them are full-fledged analogues of Crestor, even though they are produced by different companies and are sold under different trade names.
They are identical to it in terms of the active substance and, of course, the principle of action, but excipients and dosages may differ. Therefore, special attention should be paid to how many mg of the active substance are contained in one pill of generic medicine. Typically, pills are available in dosages of 10, 20, and 40 mg. It should be taken into consideration that the initial dosage may be 5 or 10 mg, and the maximum should not exceed 40 mg.
What Is More Profitable And Safe: Branded Crestor Or Its Generic?
There is no doubt that branded Crestor, which is manufactured by the large English pharmaceutical company AstraZeneca UK Ltd., is an incomparably more famous medicine than any of its analogues. Many consumers are accustomed to trusting the products of this eminent company and are suspicious of cheaper products from other pharmaceutical companies, often based in different countries, from Hungary to India. However, it should be kept in mind that there is no fundamental difference between the original medicine and its generics. Of course, generics may have less beautiful packaging, they are not advertised on TV, but in essence they are the same as their prototype. This medicine is rarely faked, but you should avoid buying generics sold not in licensed pharmacies, but in ordinary stores or on questionable websites. Under these conditions, the acquisition of a generic Crestor is no less safe than the purchase of a branded drug.
It should also be taken into account that, although the prices for Crestor Generic are significantly more affordable than for the original drug, the maximum benefit can be achieved mainly by buying a large number of tablets at a time.You can buy generics of this medicine both in ordinary pharmacies and online, and even making a purchase in a foreign online pharmacy should not be any difficulty if a particular pharmacy conducts delivery to the country in which you live.
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